Which supplement may have minor weight gain as a side effect?

Creatine is known to potentially cause minor weight gain as a side effect due to its ability to enhance water retention in the muscles. When creatine is taken as a supplement, it increases the availability of phosphocreatine, which assists in the production of ATP during high-intensity exercise. This increased phosphocreatine can lead to greater hydration of muscle cells, resulting in a short-term increase in body weight.

Furthermore, creatine may also contribute to increased muscle mass over time by supporting higher levels of training intensity and leading to greater adaptations in muscle tissue. This is particularly beneficial for athletes seeking to improve strength and performance. While weight gain can vary among individuals, it is generally recognized that creatine supplementation often results in some degree of weight increase primarily due to water retention and muscle mass development.

In contrast, other supplements like glutamine, melatonin, and BCAAs tend to have different focuses and effects on the body, with less likelihood of causing noticeable weight gain. Glutamine is primarily involved in muscle recovery and immune function, melatonin is known for regulating sleep cycles, and BCAAs (branched-chain amino acids) are often used to support muscle recovery and reduce exercise-induced muscle damage, rather than directly impacting weight.